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Lions Mane Mushroom 100g

Price $61.95 RRP

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Lion's Mane Mushroom

The mushroom people choose for focus.

Lion's mane is a shaggy white mushroom you can take as a powder, capsules or an extract. It's one of the most asked-about mushrooms in our stores.

Christina Hanley, BHSc (Nutritional Medicine), Digital Experience & Content Manager, Mr Vitamins

Christina HanleyBHSc (Nutritional Medicine), Digital Experience & Content Manager
Checked this page October 2026

See what we checked

Is Lion's Mane Mushroom right for you?

Lion's mane is one of the mushrooms our naturopaths are asked about most for focus and memory. These are the questions they ask before you take it home.

A good fit if

  • Memory or mental focus is the reason you're buying it
  • You're comfortable with evidence that's real but comes from small trials
  • You want a label that names Hericium erinaceus and gives a gram amount
  • You're happy buying it as a food, since it can't carry an Australian health claim

Check with us first if

  • You're having, or have had, cancer treatment. A review of case reports in people with cancer found mushroom products were the ones most often linked to severe reactions, mostly allergic. Talk to your treating team.
  • You take a medicine that affects your immune system or thins your blood. We haven't found a human study on how lion's mane interacts with these, so we won't guess either way.
  • You're pregnant or breastfeeding. No trial included pregnant or breastfeeding women, and there's no Australian rule setting a warning either way. That doesn't mean it's proven safe.
  • It's for a child. There's no safety information for children.
  • You're hoping it will prevent or treat dementia or mild cognitive impairment. The trials measured test scores in a research setting, not a diagnosis or a cure, so talk to your doctor about this.

How the forms compare

  • Fruiting-body powder or supplement. Best known for: The form used in the strongest human trials on thinking and memory. Absorption: Trial doses ran 1.8 to 3 g a day; absorption itself wasn't measured. Typical use: The usual pick if thinking and memory are why you're buying.
  • Mycelium extract (erinacines). Best known for: Erinacines, the compounds with the strongest lab data on nerve growth. Absorption: That nerve-growth evidence comes from lab and animal work, not human trials. Typical use: A fair choice, as long as you know the erinacine research is still early-stage.
  • Hot-water or concentrated extract. Best known for: A stronger dose in a smaller capsule than raw powder. Absorption: Not measured separately in the research we hold. Typical use: Handy if you'd rather not mix a powder.
  • Mushroom coffee or blend. Best known for: Lion's mane blended into a drink rather than taken on its own. Absorption: Blends rarely state how much lion's mane they contain, so you can't compare them to the trials. Typical use: If the research is why you're buying, a single-mushroom product is the better pick.

Common questions

Is lion's mane approved in Australia?

Not as an ingredient in listed medicines. Hericium erinaceus isn't on Australia's permitted ingredients list, so it's legally sold here as a food instead. That means it can't carry an AUST L number or a permitted health claim, which is why we talk about the research rather than make a claim.

Does lion's mane actually work for focus?

There's a real but modest signal. A 16-week trial in older adults with mild cognitive impairment found test scores rose on 3 g a day and fell again after stopping. Another small trial found faster mental processing an hour after a single 1.8 g dose, though its 28-day stress result wasn't significant. Both trials were small.

Fruiting body or mycelium, which is better?

Neither is a clear winner. Most of the positive human trials used a dry powder or supplement described as fruiting body, but the erinacines with the strongest nerve growth lab results come from the mycelium. Check the label says which part was used and gives a gram amount, not a vague "proprietary blend".

How much, and when

Reference values. There's no Nutrient Reference Value for lion's mane. It's a mushroom, not an essential nutrient, so the NHMRC doesn't set one.

Typical supplemental range. The human trials we've reviewed used 1.8 to 3 g a day. The strongest one used 3 g a day, taken as four 250 mg tablets of 96% dry Yamabushitake powder three times a day, for 16 weeks. A smaller pilot trial used 1.8 g a day. Australian products usually sit in that range. These figures are for context, not a recommendation.

Upper level. None is set. Lion's mane isn't on Australia's permitted ingredients list at all, so there's no Australian limit to quote, high or low.

Worth knowing. Check the label names Hericium erinaceus, says which part of the mushroom is used and gives a gram amount, not just "proprietary blend". What you need depends on your age, diet and health, so talk to one of our naturopaths.

Food sources

Food first, where the diet allows it.

  • Lion's mane itself: not commonly eaten as everyday food here; taken as a powder, capsule or extract
  • Shiitake, oyster and enoki: culinary sources of the same (1,3)(1,6)-beta-D-glucan fibre

Before you start

If any of these sound like you, talk to one of our naturopaths or your doctor before you start.

  • You're allergic to mushrooms or mould. Allergic reactions are a recognised side effect of lion's mane, though often unreported, and allergy was the main cause in severe cases reviewed in people with cancer using mushroom products.
  • You have cancer. Mushroom health-food products were behind most of the severe reactions reported in people with cancer. Check with your treating team first.
  • You're pregnant or breastfeeding. None of the trials we hold included pregnant or breastfeeding women, and there's no Schedule 1 entry to set a warning either way.
  • It's for a child. No safety position has been set for lion's mane in children.
  • You take immunosuppressants, blood thinners or transplant medicine. No human interaction studies exist, so we can't say either way.
  • If you take prescription medicines, check with your doctor, pharmacist or our naturopaths before you start.

The evidence, and its limits

  • A 2025 systematic review linked lion's mane to a small rise in adults' scores on thinking and memory tests. (PubMed 40959699)
  • In a 16-week trial, 3 g a day lifted older adults' thinking scores, which fell again after they stopped. (PubMed 18844328)
  • In one small trial, a single 1.8 g dose sped up mental processing within an hour. (PubMed 38004235)
  • A 2024 review of 101 trials ranked lion's mane among the most promising ingredients. (PubMed 37561965)
  • In that same small trial, the 28-day stress result wasn't significant, and the authors urged caution because the group was small. (PubMed 38004235)
  • Mood benefits for lion's mane and related mushrooms have only been seen in lab and animal work so far, not confirmed in people. (PubMed 40289452)

How it works

Lion's mane contains compounds called erinacines and hericenones. In lab and animal studies, these switched on nerve growth factor activity, a signal nerve cells use to keep working well. That hasn't been measured in people. What we do have in humans is a handful of small trials looking at whether lion's mane changes scores on thinking tests. The best of them gave 30 older adults with mild cognitive impairment 3 g a day for 16 weeks. Their scores rose over that time, then fell again within four weeks of stopping. That drop after stopping is what makes the result believable, even though it's one small trial. Because it's sold here as a food rather than a listed medicine, you won't see a health claim on the label. The human trials used about 1.8 to 3 g a day.

The Australian rules

Lion's mane isn't on Australia's permitted ingredients list (Schedule 1, 5,285 items) for listed medicines. That means it can't be an ingredient in an Australian listed medicine, so no product can carry an AUST L number for it and no permitted health claim may be attached to it. It's sold legally here as a food or food powder instead, under the Food Standards Code. Not being on Schedule 1 doesn't ban the mushroom itself, only its use in a listed medicine.

Read the instrument: Permissible Ingredients Determination.

Not sure this is the right form for you? Ask one of our naturopaths. It is free and takes 10 minutes.

Always read the label and follow the directions for use. General information only, and not a substitute for advice from your doctor or one of our naturopaths.

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