Micronutrition

SB Floraid (Saccharomyces Boulardii)

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Saccharomyces boulardii, a subspecies of S. cerevisiae, is a probiotic yeast that facilitates healthy digestive function, supports beneficial intestinal flora, and maintains the integrity of mucous linings within the digestive system. Additionally, it boosts healthy immune system function, reduces the likelihood of symptoms associated with traveller's diarrhoea, and alleviates diarrhoea in adults and children.

Product Strengths

Carefully selected botanical and nutritional ingredients
Formulated by experienced practitioners
Manufactured to strict quality standards

Ingredients

Saccharomyces cerevisiae (boulardii) 500mg, CFU equivalent: 10 billion CFU per capsule

Dosage: Per capsule (take 1-2 capsules daily): Saccharomyces boulardii 500mg delivering 10 billion CFU

Allergens

Always review label for full list of ingredients.

Suggested Use

for recommended dosage and usage instructions

TGA Listing

AUST L 406710

Storage

Store in a cool, dry place away from direct sunlight. Keep container tightly sealed.

Always read the label and follow the directions for use. Vitamin and mineral supplements should not replace a balanced diet.

Ingredients

Saccharomyces cerevisiae (boulardii) 500 mg (10 billion CFU)

Suggested dose

Adults: To maintain healthy digestive system function, take 1 capsule twice a day. To reduce the occurrence of traveller's diarrhoea symptoms, take 2 capsules once or twice daily, or as directed by your health professional.

Children 2 months - 17 years: To reduce diarrhoea, take 1 capsule once or twice daily, or as directed by your health professional. For children unable to swallow capsules, empty the content and mix with a small amount of food or liquid and consume promptly.

Warnings:
Keep out of reach of children. If symptoms persist or worsen consult your health professional. Seek medical advice if diarrhoea persists for more than 6 hours in infants under 6 months, 12 hours in children under 3 years, 24h in children aged 3-6 years and 48 hours in children over 6 years and adults. Do not use if tamper evident seal is broken or missing. Store below 25°C.

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Saccharomyces Boulardii

Why take Saccharomyces boulardii with antibiotics?

Saccharomyces boulardii is a yeast, not a bacterium, so antibiotics leave it alone. That means it keeps going and you can take it right alongside your course, not just after.

Christina Hanley, BHSc (Nutritional Medicine), Digital Experience & Content Manager, Mr Vitamins

Christina HanleyBHSc (Nutritional Medicine), Digital Experience & Content Manager
Checked this page October 2026

See what we checked

Is this the right probiotics for you?

Our naturopaths reach for this probiotic because it survives antibiotics. These are the questions they ask in store before recommending it.

A good fit if

You're about to start, or already on, a course of antibiotics and want a probiotic that survives it
You get loose stools when you travel and want the organism with trial evidence for it
You're having standard H. pylori treatment and your practitioner has suggested adding a probiotic
You're generally well, with no central line, catheter or serious immune suppression

Check with us first if

You take immunosuppressant medicine or you've had an organ transplant, because live organisms need a medical decision, not a shop one
You have any line, catheter or feeding tube in place
You're in hospital, critically ill, or recovering from major surgery
You have a weakened immune system for any other reason
You take any prescription medicine, so a quick check with your doctor, pharmacist or our naturopaths first is the sensible step

How the forms compare

Saccharomyces boulardii capsule (single organism). Best known for: The form actually used in the trials on antibiotic-related diarrhoea and H. pylori. Absorption: Not absorbed. It passes through your gut and is gone once you stop taking it. Typical use: Comes in both refrigerated and shelf-stable versions, so check the pack.
Saccharomyces boulardii sachet or powder. Best known for: Flexible dosing, mixed into water or soft food. Absorption: The same organism, delivered a different way. Typical use: Common when someone can't or won't swallow a capsule.
Multi-strain blend containing S. boulardii. Best known for: Adds bacteria alongside the yeast, often L. rhamnosus GG. Absorption: Depends on the formula and the other organisms in it. Typical use: Check the CFU for each organism, not the headline total on the front.
A bacterial probiotic such as L. rhamnosus GG. Best known for: The alternative when a central line or a weakened immune system rules out a live yeast. Absorption: Not absorbed; it works in the gut, much like this yeast. Typical use: Also trialled for antibiotic-related diarrhoea, with its own separate evidence.

Common questions

Why take a yeast probiotic instead of a bacterial one?

Antibiotics that target bacteria are made to kill them, including the good ones you're trying to protect. Saccharomyces boulardii is a yeast, so the same antibiotic doesn't touch it. A review of 21 trials in 4,780 people found that taking it during a course of antibiotics cut diarrhoea from 18.7 to 8.5 per cent.

Do I need to take it at a different time to my antibiotic?

No, not for the reason you might with a bacterial probiotic. Because antibiotics don't kill yeast, the trials gave it alongside the antibiotic course rather than spaced apart from it. If you're unsure about your particular prescription, ask your pharmacist.

Is Saccharomyces boulardii safe for everyone?

No. It's a live yeast, and seven published case reports describe it getting into the bloodstream of critically ill patients, most of whom had a central line in place. If you're seriously unwell, in hospital or immunosuppressed, or you have any line or catheter in place, check with us or your doctor before taking it.

How much, and when

Reference values. These don't apply. The NHMRC sets reference values for nutrients, and a yeast isn't one.

Typical supplemental range. The trials behind the main results didn't report a daily dose in the figures we have, only that it was taken for the length of the antibiotic course or the H. pylori treatment. Read the CFU count on the product you're holding rather than assuming a figure.

Upper level. There isn't one. Australia's permitted ingredients list (Schedule 1, item 4409) sets no maximum daily dose, and no NHMRC Upper Level applies.

Worth knowing. What you need depends on your age, diet and health, so talk to one of our naturopaths.

Food sources

Food first, where the diet allows it.

Fermented dairy such as yoghurt and kefir: not a source. Those products carry lactic acid bacteria, a different kind of organism entirely
Fermented foods generally: not a reliable source. This yeast isn't a standard fermentation culture in retail foods
Everyday diet: no verified food source for this organism is held in this register. A supplement is the practical route if you want it specifically

Before you start

If any of these sound like you, talk to one of our naturopaths or your doctor before you start.

Central venous catheters, feeding tubes or other long-term lines. Case reports describe this yeast getting into the bloodstream of critically ill patients, most with a line in place.
A severely weakened immune system, active chemotherapy, or immune-suppressing medicine after a transplant. Don't take it without specialist approval.
Critical illness, being in hospital, or recent major surgery. Check with your medical team first.
An existing or suspected bloodstream infection. Check with your doctor first.
Fever, chills or feeling unexpectedly worse while taking it. Stop and get medical advice promptly.
If you take prescription medicines, check with your doctor, pharmacist or one of our naturopaths before you start.

The evidence, and its limits

A meta-analysis of 21 trials in 4,780 people found antibiotic-related diarrhoea fell from 18.7 to 8.5 per cent. (DOI record)
Added to standard H. pylori treatment, it raised clearance rates from 71 to 80 per cent. (DOI record)
The same H. pylori trials found roughly half the treatment side effects, including diarrhoea and nausea. (DOI record)
That benefit for antibiotic-related diarrhoea held for children and adults, but only children also had less C. difficile diarrhoea. (DOI record)
Schedule 1 lists it as Saccharomyces cerevisiae (boulardii), item 4409, with no strain conditions or dose cap. (Schedule 1, item 4409)
Seven case reports describe this yeast getting into the bloodstream of critically ill patients, most of whom had a central line. (DOI record)

How it works

Antibiotics that target bacteria work by damaging bacterial cell walls or the parts that make their proteins, so they leave a yeast alone. That's why Saccharomyces boulardii is used differently from other probiotics. While a course of antibiotics is clearing out your gut bacteria, good and bad together, this yeast keeps passing through and taking up space that unwelcome organisms would otherwise move into. It isn't absorbed, and it doesn't settle in for good. Like every probiotic, it works while you're taking it and clears out of your system once you stop, which is the honest answer to how long any of these strains stay.

The Australian rules

Saccharomyces boulardii is allowed in Australian listed medicines. It's on Australia's permitted ingredients list (Schedule 1, Determination No. 2 of 2026) as item 4409, SACCHAROMYCES CEREVISIAE (BOULARDII), with no special conditions, warning statements or dose cap. It's one of the few probiotics where the official name points to this exact organism, rather than a broad species entry that could cover several different strains under one label. That's worth knowing: Lactobacillus rhamnosus, for example, is regulated as a species, so a label reading 'Lactobacillus rhamnosus' doesn't tell you which strain is inside. A boulardii label naming Saccharomyces cerevisiae (boulardii) names the same organism the list itself names. Being allowed isn't the government endorsing any product, and on its own it says nothing about whether a product works.

Read the instrument: Schedule 1, item 4409.

Not sure this is the right form for you? Ask one of our naturopaths. It is free and takes 10 minutes.

Saccharomyces Boulardii is one form of Probiotics. Always read the label and follow the directions for use. General information only, and not a substitute for advice from your doctor or one of our naturopaths.

SB Floraid (Saccharomyces Boulardii)

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Terms and Conditions

Description

Product Strengths

Ingredients

Allergens

Suggested Use

TGA Listing

Storage

ingredients

suggested dose

Product Strengths

Ingredients

Allergens

Suggested Use

TGA Listing

Storage

Ingredients

Suggested dose

Why take Saccharomyces boulardii with antibiotics?

Is this the right probiotics for you?

Why take a yeast probiotic instead of a bacterial one?

Do I need to take it at a different time to my antibiotic?

Is Saccharomyces boulardii safe for everyone?

How much, and when

Before you start

The evidence, and its limits

Reviews and Q&A

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