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Liposomal Vitamin D3 1000IU Sublingual Tablet

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Vitamin D3

Your body can't use the calcium you eat without vitamin D, and D3's the form your own skin makes in sunlight.

Most D3 sold here starts out as lanolin from sheep wool, and the vegan version's made from lichen instead. It's the same molecule either way. What trips people up isn't the source, it's the units. Micrograms in the rules, international units on the label.

Christina Hanley, BHSc (Nutritional Medicine), Health Content Lead, Mr Vitamins

Christina HanleyBHSc (Nutritional Medicine), Health Content Lead
Checked this page September 2026

See what we checked

Is this the right vitamin d for you?

Choosing D3 over D2 is usually the easy part. The questions worth asking are about the source, the units on the label and everything else you are already taking.

A good fit if

  • You want the vitamin D form with the best evidence for raising and sustaining 25-hydroxyvitamin D
  • You are vegan or vegetarian and need colecalciferol from lichen rather than from sheep-wool lanolin
  • You are comparing labels across micrograms and international units and want to convert properly before choosing
  • Your doctor has set a maintenance dose after a blood test and you are looking for a product that matches it
  • You take it with a meal containing some fat and want a format built for that

Check with us first if

  • Taking thiazide diuretics. Combining them with vitamin D raises the risk of high blood calcium.
  • Taking digoxin or another cardiac glycoside. Effects may be accentuated when vitamin D is taken with calcium.
  • Taking anticonvulsants, barbiturates, corticosteroids, orlistat or a statin. Each can alter vitamin D levels or be altered by them.
  • Coeliac disease, Crohn's disease, cystic fibrosis, untreated malabsorption or past bariatric surgery. Absorption of a fat-soluble vitamin is unpredictable.
  • Kidney disease, or a history of kidney stones. Dose and monitoring are a medical decision.
  • Pregnant or breastfeeding. Set the dose with your midwife or doctor.
  • Buying for an infant or child. The Upper Level under 12 months is 25 µg a day, which one adult capsule reaches on its own.
  • Already taking a multivitamin, calcium tablet, fish oil, bone formula or immune formula. Check every label before adding another D3.
  • Considering a 2,000 IU or 5,000 IU product from an overseas site. Those have not come through the Australian listed-medicine pathway and are not TGA-regulated for quality.
  • Taking any prescription medicine at all. A quick check with your doctor, pharmacist or our naturopaths first is the sensible step.

How the forms compare

  • Lanolin-derived D3 in an oil-filled capsule. Best known for: The default Australian product: colecalciferol suspended in an oil such as olive or sunflower. Absorption: Fat-soluble and already dissolved in oil, which is the simplest way to take a fat-soluble vitamin. Typical use: One capsule daily, most often 1,000 IU (25 µg), with a meal.
  • Lichen-derived (animal-free) D3. Best known for: The vegan and vegetarian option, and the choice for anyone avoiding sheep-derived lanolin. Absorption: Chemically identical colecalciferol; lichens have been shown to contain genuine vitamin D3, not only D2. Typical use: Capsules and drops at the same strengths as lanolin-derived products, usually at a higher price.
  • Oral spray or liquid drops. Best known for: Flexible dosing and an option where swallowing a capsule is difficult. Absorption: Still needs fat for absorption; the oil or emulsifier base matters more than the spray action. Typical use: One to a few sprays or drops daily; check the label for IU per spray, not IU per bottle.
  • Dry D3 powder in a tablet or blend. Best known for: D3 built into calcium tablets, multivitamins, immune formulas and bone products. Absorption: Absorbed less predictably without fat in the meal than an oil-based capsule. Typical use: Often a small dose you did not go looking for. Add up every product you take.
  • High-strength D3 above 1,000 IU. Best known for: 5,000 IU and similar strengths, common overseas and on international websites. Absorption: No different per microgram. The issue is the total daily amount, not the uptake. Typical use: Cannot be supplied as an Australian listed medicine at that strength; belongs in a conversation with your doctor after a blood test.

Common questions

Is vitamin D3 better than vitamin D2?

For raising the blood marker, most evidence says yes. NIH states D3 increases serum 25-hydroxyvitamin D more and maintains higher levels longer. A meta-analysis of seven trials in 1,016 adults found D3 raised it 15.2 nmol/L further than D2. But that advantage came from single large doses, and with daily dosing the difference was not statistically significant.

How many IU is 25 micrograms of vitamin D3?

Exactly 1,000 IU, because one microgram of vitamin D equals 40 international units. The same arithmetic makes 10 µg equal 400 IU and 50 µg equal 2,000 IU. Australian regulation is written in micrograms and Australian labels are printed in international units, so converting first is the only way to compare two products fairly.

Is vitamin D3 vegan?

Not usually. Standard D3 is made by irradiating 7-dehydrocholesterol obtained from lanolin, which comes from sheep wool. An animal-free version sourced from lichen is available and is the same colecalciferol molecule, so it is not a weaker product. Vitamin D2 from yeast or UV-exposed mushrooms is vegan by default but is a different form.

Why do Australian vitamin D3 supplements stop at 1,000 IU?

Because the Permissible Ingredients Determination caps a listed medicine for internal use at 25 micrograms of vitamin D per maximum daily dose, and 25 micrograms is 1,000 IU. Higher strengths sit outside that pathway. If a blood test shows you need more, that is a conversation with your doctor rather than a shelf decision.

How much, and when

Reference values. Australia's Nutrient Reference Values are set for vitamin D as a whole rather than for D3 specifically, and they are published in micrograms while almost every Australian label prints international units. That mismatch is where most dosing confusion starts. The conversion is fixed: 1 µg = 40 IU. So the adult Adequate Intake of 5 µg is 200 IU, the 51–70 figure of 10 µg is 400 IU, and the 15 µg figure from age 71 is 600 IU.

Typical supplemental range. Australian D3 products cluster at three strengths. 400 IU (10 µg) is the usual infant and children's drop. 1,000 IU (25 µg) is the standard adult capsule and also the legal ceiling for a listed medicine, which is why so many products land on exactly that number. Anything labelled 2,000 IU or 5,000 IU has not come through the Australian listed-medicine pathway at that strength.

Upper level. The NHMRC Upper Level of Intake for vitamin D is 80 µg/day, which converts to 3,200 IU, from age one onward including pregnancy and breastfeeding. For infants under 12 months it is 25 µg/day, 1,000 IU, so an adult capsule is at the infant ceiling in a single dose. NIH reports vitamin D toxicity as typically involving serum 25-hydroxyvitamin D above 375 nmol/L.

Worth knowing. The practical rule is to convert before you compare. A 1,000 IU capsule, a 25 µg capsule and a 0.025 mg capsule are the same dose written three ways, and a label that mixes units is worth a second look. Your needs depend on your age, diet and health circumstances. Talk to one of our naturopaths.

Food sources

Food first, where the diet allows it.

  • Cod liver oil and oily fish such as salmon, trout and herring: the main dietary sources of D3 specifically (vitamin D in animal foods is D3, not D2)
  • Egg yolk and liver: small amounts of D3; the yolk carries it, the white does not
  • Mushrooms exposed to ultraviolet light: a useful vitamin D source, but it supplies D2, not D3 (relevant if the D3-versus-D2 difference matters to you)
  • Fortified milks, plant milks, margarines and cereals: may be fortified with either D3 or D2 (the ingredient list will say colecalciferol or ergocalciferol)
  • Sunlight on bare skin: not a food, but it is the body's own D3 route and the reason the Australian intake figures are set low

Before you start

This list is the part of the page we will not shorten. If any of it applies to you, talk to one of our naturopaths or your doctor before starting.

  • Hypercalcaemia, hypercalciuria or any condition causing them. Contraindicated.
  • Hypervitaminosis D. Contraindicated.
  • Nephrolithiasis (kidney stones) and severe renal impairment. Contraindicated outside medical direction.
  • Hypersensitivity to any product ingredient. Contraindicated.
  • Long-term daily doses above 1,000 IU. Serum calcium, urinary calcium and renal function should be monitored.
  • Unit confusion. 25 µg equals 1,000 IU; a label read in the wrong unit is a 40-fold dosing error in either direction.
  • Infants under 12 months. The Upper Level is 25 µg (1,000 IU) per day, the same as one standard adult capsule.
  • Thiazide diuretics. Increased risk of hypercalcaemia.
  • Digoxin and other cardiac glycosides. Effects may be accentuated with vitamin D plus calcium.
  • Anticonvulsants and barbiturates. May reduce vitamin D effectiveness.
  • Corticosteroids. Impair vitamin D metabolism and calcium absorption.
  • Orlistat. Reduces absorption of fat-soluble vitamins.
  • Statins. Bidirectional interaction reported via shared metabolic pathways.
  • Malabsorption states: coeliac, Crohn's, cystic fibrosis, liver disease, bariatric surgery.
  • Pregnancy and breastfeeding. Dose to be set with a midwife or doctor.
  • Stacking. D3 also appears in multivitamins, calcium tablets, fish oils, bone and immune formulas.
  • Nausea, vomiting, constipation, thirst, polyuria, weakness, apathy or confusion. Possible hypercalcaemia; seek advice.
  • If you take prescription medicines, check with your doctor, pharmacist or our naturopaths before starting.

The evidence, and its limits

  • The vitamin D in a D3 capsule is what healthdirect describes as important for bone health and needed to absorb calcium from the intestine. (healthdirect Australia)
  • One microgram of vitamin D equals 40 international units, so 25 µg is exactly 1,000 IU. (NIH Office of Dietary Supplements)
  • Pooled across seven trials in 1,016 adults, D3 raised 25-hydroxyvitamin D by 15.2 nmol/L more than D2. (PubMed 22552031)
  • Standard D3 comes from irradiated 7-dehydrocholesterol in sheep-wool lanolin; lichen D3 is the animal-free route. (NIH Office of Dietary Supplements)
  • Lichen and lanolin D3 are the same molecule, so an animal-free product is not a weaker one. (NIH Office of Dietary Supplements)
  • That D3 advantage came almost entirely from single large boluses; with daily dosing it was not significant. (PubMed 22552031)
  • The meta-analysis authors named the small number of available trials as their main limitation. (PubMed 22552031)

How it works

Swallowed D3 is absorbed alongside dietary fat, then carried on vitamin D binding protein to the liver, where it becomes 25-hydroxyvitamin D3. The number a blood test reports. Vitamin D2 travels the same road but is handled differently: it is cleared faster, holds onto the carrier protein less tightly, and taking it measurably lowers the circulating 25-hydroxyvitamin D3 fraction. That difference in how long the storage form persists is the entire basis of the D3-versus-D2 argument. It is a pharmacokinetic difference, not a difference in what the active hormone does once the kidney has made it.

The Australian rules

Colecalciferol is a permissible ingredient in Schedule 1 of the Therapeutic Goods (Permissible Ingredients) Determination (No. 2) 2026 as item 1535, and it carries one condition, quoted verbatim below: a medicine for internal use may not exceed 25 micrograms of vitamin D per maximum recommended daily dose. Twenty-five micrograms is 1,000 IU, which is why so many Australian D3 products stop at exactly that number. Two details matter for D3 specifically. First, the ceiling is written in micrograms of vitamin D while labels are printed in international units, so the legal limit and the shelf number only look different. Second, Schedule 1 names the molecule, not its origin. Lanolin-derived and lichen-derived D3 are both colecalciferol under item 1535, so a vegan claim on a D3 product is a statement about ingredient sourcing, not a different permitted ingredient. Being a permitted ingredient means the ingredient may lawfully be used in a listed medicine; it is not a government endorsement of any product or claim.

Read the instrument: Schedule 1, item 1535.

Not sure this is the right form for you? Ask one of our naturopaths. It is free and takes 10 minutes.

Vitamin D3 is one form of Vitamin D. Always read the label and follow the directions for use. General information only, and not a substitute for advice from your doctor or one of our naturopaths.

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