NMN supplements
Your body turns NMN into NAD+, a molecule every cell uses to make energy. Studies show 250 mg a day does lift the NAD+ in your blood. What most studies have not shown is that people feel or move any better, and we would rather...
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NMN supplements Information
Our NMN range has capsules, plain powders and one slow-release tablet. The brands are Herbs of Gold, Melrose FutureLab, Switch Nutrition, Enervite, Primabolics, Nutrition Care and Live More You.
| Format | NMN per serve | Serves per pack | Typical price |
|---|---|---|---|
| Capsules | 125 mg, 250 mg or 500 mg | 30 or 60 | About $40 to $90 |
| Powder | 500 mg per scoop | 60 | About $65 to $80 |
| Slow-release tablet | 500 mg | 60 | About $150 |
The fairest way to compare prices is the cost of each 500 mg of NMN. At current prices:
- Powders: the cheapest, at a little over $1 per 500 mg, when NMN is the only ingredient.
- Capsules and the tablet: about $1.40 to $4 per 500 mg.
- 250 mg capsules: usually cost more per milligram than 500 mg capsules.
Some products are just NMN. Others add a second ingredient:
- Melrose FutureLab NMN 500mg adds dimethylglycine (DMG).
- Nutrition Care NMN Brain Support adds the herbs Bacopa and Rhodiola.
Not every product here is a listed medicine, so read the label guide below before you buy.
What Is NMN?
NMN is short for nicotinamide mononucleotide. It is closely related to vitamin B3. Your body uses it to make NAD+, a helper molecule found in every cell. NAD+ helps your cells turn food into energy.
NMN and NAD+ are not the same thing. NAD+ itself is not allowed as an active ingredient in Australian listed medicines[2]. If a product name says NAD+, check the ingredient list to see what is really inside.
Key Benefits of NMN Supplements
Listed NMN medicines in this range carry these benefits on their labels:
- Energy: helps support energy production and energy levels.
- Wellbeing: helps support general health and wellbeing.
- Nervous system: the Melrose FutureLab formulas with DMG help support nervous system health.
- Antioxidant: Herbs of Gold NMN 250 Daily helps reduce free radicals formed in the body.
The range has practical benefits too:
- Easy dosing: capsules and tablets are measured out for you.
- Choice of format: capsules, powder or a slow-release tablet.
- Single ingredient or combination: plain NMN, or NMN with DMG or herbs.
- Value: 500 mg capsules and powders cost less per milligram than 250 mg capsules.
- Plant-based shells: several capsules use plant-based shells, so they suit vegetarians and many vegans.
Products sold as sports foods do not carry these label benefits.
Does NMN Work? What the Research Shows
Scientists are still learning about NMN in people. Here is what the biggest reviews found:
- 33 studies (2026): one team looked at 33 studies in people of NMN and similar vitamins. The results were mixed, and many studies found no clear benefit for things like fitness or blood sugar[4].
- Ten studies in older adults (2025): in adults aged over 60 on average, NMN did not improve muscle size, grip strength or walking speed[8].
- 15 studies (2026): NMN made no change to body weight, blood sugar or cholesterol[11].
- Single studies: a few reported some gains, such as walking a little further or faster[6][12]. These studies were small and short, and companies ran or paid for them.
When scientists pool all the studies together, the benefits do not show up clearly. Bigger and longer studies are still needed.
How Much NMN per Day, and for How Long?
In Australia, a listed medicine with NMN must follow these rules[2]:
- It must be swallowed, not injected.
- The label cannot say to take more than 500 mg a day.
- The label cannot say to use it for longer than 12 weeks.
- It is for adults only, and not for women who are pregnant or breastfeeding.
Many studies in older adults used 250 mg a day[8]. We have not found a study that tested 250 mg against 500 mg. So 250 mg matches much of the research, and 500 mg is the most a listed medicine here may recommend.
In 2026, Europe's food safety experts checked a man-made form of NMN for food supplements. They looked at doses up to 300 mg a day for adults, but not for pregnant or breastfeeding women[3]. That is a European opinion, not an Australian approval.
Some products sold as sports foods say you can take two 500 mg serves a day. That is twice the most an Australian listed medicine may recommend. If you are not sure how much to take, ask a practitioner or pharmacist.
NMN also counts towards your vitamin B3. A 500 mg serve of NMN gives about 180 mg of nicotinamide, a form of vitamin B3. The Australian upper limit for nicotinamide from all sources is 900 mg a day for adults[7]. Keep that in mind if you also take vitamin B3.
Capsules, Powder or Slow-Release Tablets?
- Capsules: already measured out, so they are easy to take each day.
- Powder: usually costs the least per 500 mg and mixes into water, but you need to measure each scoop carefully.
- Slow-release tablet: the Enervite sustained-release tablet lets its 500 mg out slowly instead of all at once.
- Under the tongue: some products say to hold NMN under your tongue so it works faster. In 2026, a small study tested this in 14 men. In the first hour, the amount of NMN in their blood was about the same whether they held it under the tongue or swallowed it. Only some waste products rose faster[10].
We have not found a study that compared capsules, powders and tablets with each other. Pick the one you will keep taking.
NMN vs NR, Vitamin B3 and NAD+
NMN, nicotinamide riboside (NR) and nicotinamide all belong to the vitamin B3 family. Your body can use all three to make NAD+. In Australian listed medicines, NMN is allowed at up to 500 mg a day, and nicotinamide riboside chloride at up to 300 mg a day[2].
NAD+ drips and injections are a different thing. A 2026 review found no studies that tested NAD+ drips or injections for anti-ageing or wellness and measured real results[4].
NMN Side Effects and Who Should Avoid It
Studies have tested 250 to 2,000 mg a day for up to 24 weeks. People taking NMN had no more side effects than people taking a dummy pill or no NMN. Their liver tests did not change much either[11]. Those studies lasted up to 24 weeks, so we do not know about longer use.
NMN is not for:
- children;
- women who are pregnant or breastfeeding;
- anyone who takes medicines or has a health problem, unless their doctor, pharmacist or a qualified practitioner says it is fine.
Is NMN Legal in Australia? How to Read an NMN Label
Yes, with rules. NMN has been allowed in Australian listed medicines since 10 December 2025[1]. Until 10 December 2027, there is one more rule. NMN can only go in a listed medicine if one company, SyncoZymes (Shanghai), is behind it, or has given another company permission and told the TGA[2].
- AUST L number: the product is a listed medicine on the Australian Register of Therapeutic Goods (ARTG). You can search the number on the TGA website to check.
- No AUST L number: the product is not a TGA-listed medicine. Words like "formulated supplementary sports food" describe a type of food. They are not a TGA listing.
- Purity: the TGA has a guideline that sets how pure NMN must be in listed medicines[9]. For any brand, the best proof of what is in the pack is a recent test report from an independent laboratory.
How to Choose an NMN Supplement
- Dose: 125 mg to 500 mg a serve.
- Value: compare the price per 500 mg.
- Formula: NMN on its own, or with other ingredients.
- Format: the capsule, powder or tablet you will take every day.
- Label: AUST L number, directions and warnings.
To compare the products one by one, read our practitioner comparison of NMN supplements in Australia. You can also explore our B complex vitamins and healthy ageing range.
Always read the label and follow the directions for use.
References
- Commonwealth of Australia (2025) Therapeutic Goods (Permissible Ingredients) Determination (No. 4) 2025. Federal Register of Legislation, F2025L01486. Available at: https://www.legislation.gov.au/F2025L01486/asmade (Accessed: 22 October 2026).
- Commonwealth of Australia (2026) Therapeutic Goods (Permissible Ingredients) Determination (No. 3) 2026. Federal Register of Legislation, F2026L01382. Available at: https://www.legislation.gov.au/F2026L01382/asmade (Accessed: 22 October 2026).
- EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) (2026) 'Safety of beta-nicotinamide mononucleotide (β-NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC', EFSA Journal, 24(5), e10007. Available at: https://doi.org/10.2903/j.efsa.2026.10007. Prepared at the request of the European Commission.
- Gallagher, C. and Emmanuel, O.O. (2026) 'NAD+ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence', Ageing Research Reviews, 116, 103057. Available at: https://doi.org/10.1016/j.arr.2026.103057. Funding: no funding source stated.
- Kim, M. et al. (2022) 'Effect of 12-week intake of nicotinamide mononucleotide on sleep quality, fatigue, and physical performance in older Japanese adults: a randomized, double-blind placebo-controlled study', Nutrients, 14(4), 755. Available at: https://doi.org/10.3390/nu14040755. Funding: Mitsubishi Corporation Life Sciences Ltd.
- Morifuji, M. et al. (2024) 'Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study', GeroScience, 46(5), pp. 4671-4688. Available at: https://doi.org/10.1007/s11357-024-01204-1. Funding: not stated; the authors are employees of Meiji Holdings Co., Ltd.
- National Health and Medical Research Council, Australian Government Department of Health and Ageing and New Zealand Ministry of Health (2006) Nutrient reference values for Australia and New Zealand: niacin. Canberra: NHMRC. Available at: https://www.eatforhealth.gov.au/sites/default/files/2022-04/n35-niacin_0.pdf (Accessed: 22 October 2026).
- Prokopidis, K. et al. (2025) 'The effect of nicotinamide mononucleotide and riboside on skeletal muscle mass and function: a systematic review and meta-analysis', Journal of Cachexia, Sarcopenia and Muscle, 16(3), e13799. Available at: https://doi.org/10.1002/jcsm.13799. Funding: no specific funding.
- Therapeutic Goods Administration (n.d.) Nicotinamide mononucleotide: compositional guideline. Canberra: TGA. Available at: https://www.tga.gov.au/resources/resources/compositional-guidelines/nicotinamide-mononucleotide.
- Wakabayashi, J., Higashi, S. and Morifuji, M. (2026) 'Sublingual NMN administration increases early circulating terminal catabolites 2PY and 4PY compared with oral administration in healthy adult men', Scientific Reports, 16(1), 27464. Available at: https://doi.org/10.1038/s41598-026-57552-9. Funding: Meiji Holdings Co., Ltd.
- Yang, W. et al. (2026) 'Safety and metabolism-related outcomes of oral nicotinamide mononucleotide supplementation in adults: a systematic review and meta-analysis', Nutrients, 18(14), 2251. Available at: https://doi.org/10.3390/nu18142251. Funding: no external funding.
- Yi, L. et al. (2023) 'The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial', GeroScience, 45(1), pp. 29-43. Available at: https://doi.org/10.1007/s11357-022-00705-1. Funding: Aba Chemicals Co. and Abinopharm, Inc.
Frequently Asked Questions
Is NMN legal to sell in Australia?
Yes, with conditions. NMN became a permitted ingredient for listed medicines on 10 December 2025. Until 10 December 2027 it may only be used in a listed medicine where SyncoZymes (Shanghai) is the sponsor, or has authorised the sponsor and told the TGA, so not every NMN product on sale here can lawfully be a listed medicine. The TGA's guidance of 12 August 2026 sets out what may and may not be said about it.
Why can a supplement not say it raises your NAD+?
Because no approved wording in Australia mentions NAD+ or NMN. The TGA confirmed this again in August 2026 and named phrases such as boost NAD+ levels as not permitted. You will still come across that wording in the wider market. When you do, treat it as marketing rather than an approved claim.
Does NMN actually work?
It does raise the NAD+ in your blood. Whether anything you can feel follows is the unsettled part. The studies listed on this page include a 2025 review of ten trials that found no benefit for muscle size, grip strength, walking speed or chair-stand time in adults whose average age was over 60, and one 60-day trial that did improve six-minute walking distance at higher doses. We list both.
How much NMN should I take?
Both 12-week trials on this page used 250 mg a day. In the 2025 review, every NMN trial used 250 mg a day except one, which used 2000 mg a day for four weeks and found no change. A separate 60-day trial tested 300, 600 and 900 mg and found more blood NAD+ and better six-minute walking distance at all three. Australian rules cap any listed NMN medicine at 500 mg a day, so the doses that did best in that trial are above what a listed medicine here may recommend. No study has compared 250 mg with 500 mg directly.
How long before NMN does anything?
The 12-week trials measured at 12 weeks, so 12 weeks of daily use is the honest answer to give. The NAD+ in your blood goes up within a few weeks. Australian rules also cap the recommended duration of a listed NMN medicine at 12 weeks or less.
What is the difference between NMN and NR?
Both are building blocks your body uses to make NAD+, and the TGA lists both as precursors. The 2025 review pooled the NMN trials and looked at the nicotinamide riboside trials separately, where the results were mixed. Neither showed a benefit for muscle size or strength. We stock both, and no study on this page compared them directly at the same dose.
Is NMN safe?
The trials on this page reported it was well tolerated, in groups of 36, 60 and 80 healthy adults over 60 days to 12 weeks. Those are small, short studies. Any listed NMN medicine in Australia is for adults only and not for pregnant or breastfeeding women, and healthdirect advises telling your doctor or pharmacist about supplements you take before a new medicine is prescribed.
How do I check whether a product is a listed medicine?
Look for an AUST L number on the label, then search it on the Australian Register of Therapeutic Goods. If there is no AUST L number, the product is not a listed medicine. Some are sold as formulated supplementary sports foods under the food rules; the TGA also warns that goods referring to NMN and not entered on the ARTG may be unapproved or unlawfully supplied, so the register is the check that matters.