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  • Carusos Vitamin B6 100mg
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Carusos Natural Health

Carusos Vitamin B6 100mg

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Price $19.20 Save 20% RRP $24.00

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Price $19.20 Save 20% RRP $24.00

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Vitamin B6

What does vitamin B6 do?

Vitamin B6 helps your body make brain chemicals like serotonin. When PMS leaves you moody, irritable or tired before your period, B6 is the vitamin the trials keep coming back to.

Christina Hanley, BHSc (Nutritional Medicine), Digital Experience & Content Manager, Mr Vitamins

Christina HanleyBHSc (Nutritional Medicine), Digital Experience & Content Manager
Checked this page October 2026

See what we checked

Is Vitamin B6 right for you?

Our naturopaths ask more questions about B6 than most supplements before anyone buys it. These are the questions they ask in store.

A good fit if

  • PMS brings on low mood, irritability or tiredness each month, which is the side of PMS the trials found B6 helps
  • You want a single B6 you can take on its own, rather than stacking it inside several combination products
  • You've checked your other supplements and your total B6 stays within the Upper Level

Check with us first if

  • You're pregnant and feeling sick. B6 has good support for pregnancy nausea, but the dose needs your doctor's input, and anything above 50 mg a day is over the pregnancy Upper Level.
  • You take levodopa for Parkinson's disease. Pyridoxine can make levodopa work less well, so ask your prescriber first.
  • You're buying for a child or teenager. The legal and safe limits are much lower than for adults, from 15 mg at 1 to 3 years up to 40 mg at 14 to 18.
  • You already take a multivitamin, magnesium, zinc, iron or stress formula. The TGA names these as places B6 hides, so add up your total first.
  • You're on the pill. People taking oral contraceptives are more likely to run low in B6, so raise it with us rather than taking a high dose on your own.
  • You've had a transplant, or you take any prescription medicine at all.

How the forms compare

  • Pyridoxine hydrochloride. Best known for: The standard, stable form, and the one used in almost every B6 trial, for PMS, pregnancy nausea and homocysteine. Absorption: Your body has to convert it to the active form first. We found no head-to-head human absorption trial against P5P. Typical use: Tablets and most multivitamin, magnesium and B-complex formulas. Labels show it as pyridoxine, so 50 mg of the salt is about 41 mg of B6.
  • Pyridoxal 5'-phosphate (P5P), including the monohydrate. Best known for: The active form itself, so it skips the conversion step. Absorption: It looked less toxic to nerve cells in lab tests, but no human trial shows it works better than pyridoxine. Typical use: Practitioner and 'activated' products. The same legal caps, label warning and 2027 pharmacy rule apply as for pyridoxine.
  • Pyridoxamine. Best known for: A third natural form, studied overseas in kidney research. Absorption: Not relevant here, because it isn't allowed in Australian listed medicines. Typical use: Not sold as a listed medicine in Australia. We mention it so overseas studies and products make sense.

Common questions

Can you take too much vitamin B6?

Yes. It's the exception to the idea that water-soluble vitamins are always safe. Too much B6 can damage the nerves that carry feeling in your hands and feet (peripheral neuropathy), and the TGA had 250 Australian reports of it as of 31 October 2025. The adult Upper Level is 50 mg a day from all sources, and symptoms can take years to appear.

Is P5P better than ordinary vitamin B6?

Not on the human evidence so far. P5P is the active form, so it skips a conversion step, and it looked less harmful to nerve cells in laboratory tests. But no human trial shows it works better, and almost every positive B6 trial used pyridoxine hydrochloride. Legally it's treated the same, with the same limits and warning.

Why does my magnesium have a nerve warning on it?

Because it contains more than 10 mg of vitamin B6 in a daily dose. Australian rules require a warning on any listed medicine above that level, telling you to stop taking it and see your healthcare practitioner if you get tingling, burning or numbness. It's a reminder to add up the B6 across everything you take.

How much, and when

Reference values. The NHMRC sets the Recommended Dietary Intake at 1.3 mg a day for adults aged 19 to 50. It's 1.7 mg for men and 1.5 mg for women over 50, 1.9 mg in pregnancy and 2.0 mg while breastfeeding. Children need 0.5 mg at 1 to 3 years, 0.6 mg at 4 to 8 and 1.0 mg at 9 to 13.

Typical supplemental range. Multivitamins usually contain 10 to 25 mg, and B-complex and magnesium formulas 25 to 50 mg. The PMS trial that found a benefit used 50 mg a day, and most of the pregnancy nausea trials used 10 to 40 mg.

Upper level. The adult Upper Level is 50 mg a day from all sources combined, as pyridoxine. It's lower for children: 15 mg at 1 to 3 years, 20 mg at 4 to 8, 30 mg at 9 to 13 and 40 mg at 14 to 18. For babies under 12 months no Upper Level can be set, and the NHMRC says their B6 should come from breast milk, formula or food only. Signs of too much can take years to show. In one study, people had been taking supplements for an average of 2.9 years.

Worth knowing. The number that matters most isn't on any one label. It's the total across everything you take, because B6 turns up in multis, magnesium, zinc, iron and stress formulas. What you need depends on your age, diet and health, so talk to one of our naturopaths.

Food sources

Food first, where the diet allows it.

  • Organ meats: listed by the NHMRC (no verified per-serve figure yet)
  • Muscle meats: listed by the NHMRC (no verified per-serve figure yet)
  • Breakfast cereals: listed by the NHMRC (no verified per-serve figure yet)
  • Vegetables: listed by the NHMRC (no verified per-serve figure yet)
  • Fruits: listed by the NHMRC (no verified per-serve figure yet)

Before you start

If any of these sound like you, talk to one of our naturopaths or your doctor before you start.

  • Tingling, burning or numbness in your hands or feet. Stop and see a practitioner as soon as possible; too much B6 causes nerve damage that affects feeling.
  • Combining products. Multivitamins, magnesium, zinc, iron and stress formulas can all contain B6, so add up your total.
  • Long-term use. Nerve damage can take years to appear; in one study it took 2.9 years on average.
  • Levodopa. Pyridoxine can make it work less well, so ask your prescriber.
  • Isoniazid. Your treating doctor prescribes pyridoxine alongside it; it's not something to buy off the shelf for this.
  • The contraceptive pill. It's linked to lower blood B6; talk it through with a practitioner.
  • Tacrolimus and kidney transplant. Low B6 is common; see your practitioner rather than self-treating.
  • Pregnancy. Doses above 50 mg a day exceed the Upper Level; using it for nausea needs your doctor's input.
  • Children and teenagers. Upper Levels are 15, 20, 30 and 40 mg, depending on age.
  • Babies under 12 months. B6 should come from breast milk, formula or food only.
  • If you take prescription medicines, check with your doctor, pharmacist or one of our naturopaths before you start.

The evidence, and its limits
  • A 2025 review of 31 trials found B6 consistently eased the emotional symptoms of PMS, like mood and irritability. (DOI record)
  • Only 1 of those 31 PMS trials was rated at low risk of bias, so the evidence is thin. (DOI record)
  • A 2023 review of 18 studies found pyridoxine significantly improved nausea scores in pregnancy. (DOI record)
  • In a trial of 1,599 patients, pyridoxine alone didn't clearly beat placebo for pregnancy nausea, but the combination with doxylamine did. (DOI record)
  • As of 31 October 2025, the TGA had 250 Australian reports of nerve damage (peripheral neuropathy) from vitamin B6. (Therapeutic Goods Administration)
  • A review of 21 studies found higher B6 levels gave no significant benefit for thinking or dementia risk. (DOI record)

How it works

Once your body converts it to its active form, pyridoxal 5'-phosphate (P5P), B6 works as a helper for more than a hundred enzymes, and most of them handle amino acids, the building blocks of protein. That includes making the brain chemicals serotonin, dopamine and GABA, building haem for red blood cells, and clearing homocysteine from your blood. Think of it as the spanner a lot of different workers borrow from the same toolbox. The catch is that conversion step. At high intakes, the B6 circulating in your blood appears to block the very enzyme that activates it, and that's the leading explanation for why too much B6 can damage the nerves that carry feeling.

The Australian rules

There's no entry called vitamin B6. Instead, Australia's permitted ingredients list (Schedule 1, Determination No. 2 of 2026) includes three specific forms: PYRIDOXAL 5-PHOSPHATE at item 4234, PYRIDOXAL 5-PHOSPHATE MONOHYDRATE at item 4235 and PYRIDOXINE HYDROCHLORIDE at item 4236. All three have the same conditions. Each must state its content as pyridoxine, worked out by molecular weight. Each has an age-based cap on the maximum daily dose. And each needs a compulsory nerve warning on the label once a daily dose goes over 10 mg. Pyridoxamine isn't in Schedule 1. Separately, the TGA has changed the Poisons Standard. From 1 June 2027, products taken by mouth with more than 50 mg per recommended daily dose become Pharmacist Only, and more than 200 mg needs a prescription. Products with 50 mg or less stay on general sale. The TGA cited 250 reports of nerve damage (peripheral neuropathy) as of 31 October 2025. Being allowed means it can legally be used in a listed medicine. It isn't the government endorsing any product or claim.

Read the instrument: Schedule 1, item 4234.

Not sure this is the right form for you? Ask one of our naturopaths. It is free and takes 10 minutes.

Always read the label and follow the directions for use. General information only, and not a substitute for advice from your doctor or one of our naturopaths.

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