St John’s Wort (15 products)

St John’s wort (Hypericum perforatum) has been traditionally used in western herbal medicine for mild anxiety, nervous restlessness, mood imbalance, tiredness, loss of appetite and trouble sleeping. It’s also can be used to treat heart palpitations, moodiness, the symptoms of attention deficit-hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), seasonal affective disorder (SAD) and symptoms of menopause and PMS.


Many studies show that St John’s wort supplements may help fight mild to moderate depression and anxiety and has fewer side effects than most other prescription antidepressants.


The flowers are used to make St john’s oil, liquid extracts, pills, and teas. People have been using St. John’s wort for centuries. St John’s wort is so named because the plant opens its yellow flowers in the northern hemisphere around the feast day of St John the Baptist in late June. Wort is an old English word for plant.


St John’s wort anxiety treatment doesn’t require a prescription and you can buy it over the counter. When choosing a St John’s wort supplement, it’s important to look for a standardised extract that contains the biologically active substances hypericin and hyperforin, which have the greatest medicinal activity. St John’s wort dosage can range from 900mg,1800mg to 3,6000mg per day.


In Australia, St John’s wort is freely available, but preparations are regulated by the Therapeutic Goods Administration (TGA), which has warned that the strength of active ingredients may vary between preparations and that drug interactions are also possible with other medicines.


Some of the drugs that St John’s wort interacts with include:

  • antidepressants;
  • HIV medicines;
  • medicines that modify the immune system that are often used in people who have had organ transplants (e.g. cyclosporin, tacrolimus);
  • warfarin (a blood thinning agent);
  • certain medicines used in the treatment of heart disease (e.g. digoxin, nifedipine, verapamil);
  • certain cholesterol-lowering medicines (e.g. atorvastatin, simvastatin);
  • some medicines for type 2 diabetes (e.g. gliclazide);
  • anticonvulsants used in the treatment of epilepsy;
  • the contraceptive pill; and
  • migraine treatments.
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